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The hole-board test is a rodent model test for measuring head-dipping activity in experimental animals. Changes in head-dipping activity have been considered to be related to anxiety by some researchers. The hole-board apparatus consists of an enclosed space, the floor of which has sixteen holes in a grid-pattern.〔http://130.229.40.24/our-research/methodological-platforms/translational-behavioural-neuroscience/hole-board-maze/〕 The rodent, when placed in the apparatus, is free to dip its head through the holes in the floor; the frequency and duration of this behaviour, known as 'head-dipping' is thought to measure levels of neophilia.〔File and Wardill, 1975a; Ljungberg and Ungerstedt, 1976〕 Such experiments are used in the field of behavioural pharmacology.〔Pharmacological and genetic influences on hole-board behaviors in mice Kliethermes CL, Crabbe JC Pharmacol Biochem Behav. 2006 Sep; 85(1):57-65. () (list )〕 == References == 抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Hole-board test」の詳細全文を読む スポンサード リンク
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